They don't need to know anything about inks or printing to decide that they don't like a heavy, thick Plastisol print.
Of course, there are ways to make Plastisol prints that are much better than typical, just as there are ways to make them much "worse." It probably matters more if the garment is a relatively light weight, high thread count, ringspun/tri-blend sort thing and the price tag is $20+, and whether it is a design that someone will actually wear, or a gag gift that will die in the sock drawer.
I started off doing discharge, and would still be doing it, but it doesn't work for my current almost POD-like printing schedule, and I have misgivings about the fumes. No hand at all.