I just bought this software yesterday, and I was disappointed to find that it does not index for you; you still use Photoshop's indexing mode before you use their software, so you still have to manually tweak to get the indexing right. All the program does is separate the colors, (which you can easily do with the magic wand in photoshop,) and then export the layers as an EPS file so that you can open it with Illustrator, etc which is useful for adding high resolution postscript text, etc. When I went back and looked at their advertising I saw that they don't ever actually say that their program does better indexing than Photoshop, but that "Our extensive manual will easily explain the many secrets to color reduction". And in another place: "You can simply pick the colors right from the image, and the image redraws in just those colors that will be printed. The file is then exported to Adobe Illustrator or Corel Draw in just seconds, where each custom color has it's own layer and can be printed as
postscript separations." The blue part is just using Photoshop to do index colors, but I thought they were saying that the software helped in some way to get better results, but you don't even use the Screenprint Separator software until AFTER those steps. The program only works on files that are already indexed.
They do give a lot of useful information in the manual that I haven't seen anywhere else although it could be better organized. And it does save a lot of time if you want to add postscript items to your image.