Real screen opener is super nasty stuff, and no, rubbing (isopropyl) alcohol doesn't even touch it as far as efficiency goes. It's not good for stencils, as it will sink in like water will, and make them soft and easily damaged. I think it's great for squeegees, floodbars, and cleaning up tabletops or floors, etc... but not screens.
You'll have a hard time replacing screen opener with something safer that is just as effective--but a good low VOC press wash will be your best bet. Something like Plastisolve 842 from Easiway, one of the TS (or maybe their eco line?) from CCI, or one of the Franmar chems--not familiar with them. Unfortunately, oil bases need solvents to clean them--and even the 'green derived' press washes are still bad for you. Read the MSDS and instructions on anything you use, and follow them.