No. The ink I use as my standard white has some bleed resistance. Low bleed whites tend to cost a little more than cotton whites, and I think tend to be a little thicker, but there's no reason you can't use them on cotton shirts.
um well the low bleed white i use requires a lower cure temp of 140c where as my standard plastisol requires a temp of 160c....I have made the mistake of using the low bleed and heatset it at 160c and it comes out with bubbles in it.
The best thing to do is find and read the tech data sheet. Generally you will have little to no problems printing low bleed ink on cotton, but it is always best to double check the manufacturers recommendations.
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