@divine-German Village is cool, Schmidt's is like a world renowned German sausage house, they make everything in house and their cream puffs should be illegal. There are also a couple cool "beverage" spots in GV. The Arena District has some cool spots, but depending on if anything is going on at the Arena, it may be a little slow. The Arena district is in walking distance of the convention center where ISS is going on so that's handy. A couple miles the opposite direction is The Ohio State University campus area, and I probably don't have to say it, but there is no lack of great restaurants and such in that area.
You get the idea, and I didn't even get into the Lennox or Easton or Polaris areas, plenty of cool places to eat and hang all over the city.
And it just occurred to me, that Saturday is Cinco de Mayo, so there will be all kinds of craziness going on.