Depending on the ink and shirt weight you use, it may or may not bleed through. Also depending on the ink, printing on the inside may be uncomfortable on the skin (scratchy or hot & sweaty).
If you have any printed shirts like the one you would be printing, turn it inside out and see if you can see through it.
If you have any printed shirts like the one you would be printing, turn it inside out and see if you can see through it.