We have had hands on experience with both. The Brother requires less training. You can put on operator on it with less than 30 minutes of training an be printing shirts at a productive pace. The Epson is a good machine, with a lot of customization options that can be confusing for operators. The Brother had more up-time for us. It is important to make sure you have a local technician to support you. Also, make sure you are printing daily or you can have chronic issues with any machine.