No matter what you do in Corel, Illy or photoshop as long at the person separating the art knows what they are doing and the printer as well you can do what ever you want. A seasoned separator and printer can pretty much work with anything you give. Only thing I would reccomend is paying attention to your number of colors. Many designs with tons of colors can be reduced to a manageable amount being printed yet there are some limitations. Your printers total number of colors ability to print is the main one.
Smaller areas in a design can be mixed on press yet I would advise staying away from large areas. Halftones are not a problem as long as the output device an accurately print them and the printer can reproduce them on both screen and press.
Smaller areas in a design can be mixed on press yet I would advise staying away from large areas. Halftones are not a problem as long as the output device an accurately print them and the printer can reproduce them on both screen and press.
