David,
I would have to agree with Shaggy, I would think it would be about the same on the Decor machine as the Cams. If I have a design with more than 2 colors or sizes, I just X out the other colors and sizes besides the 1 and 2, run the first two colors or sizes and then change out the stones and move two new colors up to the 1 and 2 position and keep the other numbers X'd out, run the design again, and so forth until the design is finished. I have run designs with as many as 10 colors or sizes. They take longer, but with a small vacuum, they aren't too bad.
Did Mesa not give you training on the machine? That is one of the things that I really love about Coldesi, they include a setup and training day on your site. Our trainer even stayed longer, because he wanted to make sure the machine was running perfect before he left. It was flipping about one stone every couple of designs and he didn't want any flipped stones at all. Mesa gave us training on our Viper at their shop, but we didn't get a trainer that was very well versed on the machine.