Are you running the paper through your conveyor or flash dryer first to dry and shrink the paper? Is this picture of a before applying ink or afterwards? It appears to be water drops. Or maybe something under the press that is lifting the paper up or down in that area. Do you have any ink on the heat platen? Anything else there that would be on the platen?
After re-reading your post for the 5th time, I'm thinking your bottom rubber mat might be getting so hot that it's sinking down around the glue that is holding the mat to the bottom of the press giving a crater like effect. Or possibly a cold spot on the platen.
Maybe slow down to give the press a chance to recoup it's heat and cool off where it needs to cool off.
After re-reading your post for the 5th time, I'm thinking your bottom rubber mat might be getting so hot that it's sinking down around the glue that is holding the mat to the bottom of the press giving a crater like effect. Or possibly a cold spot on the platen.
Maybe slow down to give the press a chance to recoup it's heat and cool off where it needs to cool off.