I understand what you are asking but I'm not personally confident that this would be worth doing (in this example). Disney would sue your *** unless you had a license and in order to get that you would need to create the proper Process type image. I don't think this idea, for various reasons including the result, would pan out well for you in Spot colour.
Piglet is actually many colours because Pooh is now CG, so piglet is various shades of mauve through to pink.
Anyway -
You can select an area in Photoshop with the magnetic lasso tool or polygonal lasso tool and then do filter/sketch/halftone pattern. Keep it selected and then do image/adjustments/colour balance and adjust it to red. Unselect.
Piglet is actually many colours because Pooh is now CG, so piglet is various shades of mauve through to pink.
Anyway -
You can select an area in Photoshop with the magnetic lasso tool or polygonal lasso tool and then do filter/sketch/halftone pattern. Keep it selected and then do image/adjustments/colour balance and adjust it to red. Unselect.