I have used Wacom since the 90's. Before that, it was a lot of hand drawing, inking and airbrushing. . . and a lot of time. The Wacom really enhances your hand/eye coordination. It is a MUST tool for digital artists today. Not saying that their are artists who still use the mouse, but once you cross over, you would find it hard to go back to the mouse.
I now use a Cintiq at home, but use the Intuos at work. I prefer the Cintiq. It's about 3 times faster, but I have no problem going back and forth between the two. I rarely sketch on paper any more. Usually in Photoshop. I'll ink in Illustrator for crisp lines, or Photoshop, depending on the style.
The image is a progression from a sketch in Photoshop. Inking in Illustrator, then back to Photoshop for airbrushing.