I would suggest putting the cd-r in the computer and see if there's a usb to serial emulator driver on it and if so run it. The artcut software I am not familiar with so I really can not help you there.
Go over to
US Cutter - Home and in the forums there is a place to post for help with different machines then they sell. Maybe someone can help you with artcut as that used to be the software they used with their plotters.