To be honest, I don't know the laser transfer process all that well. I'm still researching that aspect.
After looking at self-weeding paper, it would cost more per print to use that stuff, so in the long run you're either going to spend time cutting inkjet transfers or spend money on self-weeding laser papers. It's a tradeoff.
I know, now I'm adding even more confusion.
Personally, I'll be using Jet-Pro SofStretch for my transfers and cutting that on my Graphtec CE5000-60. I have the process down pretty well now and can easily print, cut, and press in a short amount of time.
The thing I will be doing eventually is getting a better, larger format inkjet printer. 8.5x11 is just too limiting for me.
And on that note, I have NO idea what a laser printer costs that can print 11x17 paper...
I wish I could help a little more. All I can offer is my limited opinion.